WebCCT036477 is an inhibitor of Wnt signaling. Studies show that CCT036477 does not alter b-catenin levels but blocks transcription at the b-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes. WebCCT036477 Preclinical: Actionable: In a preclinical study, CCT036477 inhibited Wnt pathway activation and growth of colorectal cancer cell lines harboring APC inactivating mutations in culture (PMID: 20610623). 20610623 APC inact mut colorectal cancer sensitive

CCT036477 VWR

WebCCT036477 is an inhibitor of Wnt signaling. It does not alter β-catenin levels but blocks transcription at the β-catenin level. CCT036477 inhibited growth in several cancer cell … WebCCT036477 is an inhibitor of Wnt signaling. It does not alter β-catenin levels but blocks transcription at the β-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes. coffee farms oahu hawaii

Sigma Aldrich Fine Chemicals Biosciences …

WebCCT036477: Catalog Number: M8243: CAS Number: 305372-78-5: 1.2 Relevant identified uses of the substance or mixture and uses advised against; Identified uses: For research use only, not for human or veterinary use. 1.3 Details of the supplier of the safety data sheet; Company: Abmole Bioscience Inc. 8300 Cypress Creek Parkway, Suite 450 Houston ... WebEfficiently mine multiple large-scale pharmacogenomic datasets. WebCCT036477. Product Type : Biochemical. Size : 5 mg. list of Pubmed id : 20610623. Product Description : Inhibits Wnt signaling via blocking transcription at the β-catenin level independent of CBP or p300. Inhibited growth in several cancer cell lines (HT29, HCT116, SW480, and SNU475). CCT036447 was also active in vivo where it blocked ... coffee far side